Produce cryo-lamellas for cryo-tomography using autoloader TEM systems.Cryo-dedicated hardware inside the DualBeam system chamber ensures optimal sample preparation while maintaining cryo conditions. Cryo specimens are mounted in dedicated Cryo-FIB AutoGrids which can be loaded into AutoLoader TEM systems.
Create thinner cryo-lamella without cutting artifacts. Ion beam milling enables creation of compression-free cryo-lamella samples for TEM tomography imaging. This method avoids artifacts such as mechanical compression inevitable for mechanical cryo-sectioning approaches using cryo-ultramicrotomes.
Improve sample preparation precision. Guided user software and Thermo Scientific™ MAPS™ correlation software makes the Aquilos Cryo-FIB easy to use, even for inexperienced users.
Assembly of a Nucleus-Like Structure During Viral Replication in Bacteria
Courtesy of Vorrapon Chaikeeratisak, Katrina Nguyen, Kanika Khanna, Axel F. Brilot, Marcella L. Erb, Joanna K. C. Coker, Anastasia Vavilina, Gerald L. Newton, Robert Buschauer,
Kit Pogliano, Elizabeth Villa, David A. Agard, Joe Pogliano
In press. Science, 2017. DOI: 10.1126/science.aal2130